![]() ![]() Polyneuropathy is the first step in the generation of diabetic foot ulcer. Life-time risk of foot amputation is 15% in patients with diabetic polyneuropathy. At the time of diagnosis, neuropathy is present in 10% of diabetic patients and overall in 50% of patients with a 25-year history of the disease. Incidences of polyneuropathy have been reported in 10–50% of patients with diabetes. Complications of DN include severe pain, loss of ambulation and increased risk of foot ulceration and amputation. This results in significant disability and morbidity. One of the most frequently-occurring microvascular complications is diabetic neuropathy (DN), of which the most common type is distal symmetrical neuropathy or polyneuropathy. DM has two types of complications: microvascular and macrovascular. Nearly 7.5% of Iranian people are affected by DM type II. More attention must be paid to elderly male diabetic patients with poor diabetes control with regard to regular foot examinations and more practical education.ĭiabetes mellitus (DM) is one of the most widespread chronic diseases in the world. Glycemic control reduces the incidence of neuropathy, slows its progression and improves the diabetic patient's quality of life. In this study, hyperglycemia was the only modifiable risk factor for diabetic neuropathy. No correlation was found with any atherosclerosis risk factor (high BP, hyperlipidemia, cigarette smoking). Statistically significant relationships were found between neuropathy and age, gender, quality of diabetes control and duration of disease (P values in the order: 0.04, 0.04, < 0.001 and 0.005). The multiple factors compared between the two groups included consumption of angiotensin converting enzyme inhibitors (ACEI), blood pressure, serum lipid level, sex, smoking, method of diabetes control and its quality. The diagnosis of neuropathy was confirmed by nerve conduction studies (nerve conduction velocity and electromyography). Michigan Neuropathic Diabetic Scoring (MNDS) was used to differentiate cases from controls. In this case-control study, 110 diabetic patients were selected from the Shariati Hospital diabetes clinic. Since neuropathy often leads to ulceration and amputation, we have tried to elucidate the factors that can affect its progression. Neuropathy is one of the most common complications of diabetes and lowers the patient's quality of life. Diabetes mellitus type II afflicts at least 2 million people in Iran.
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